Pyridazines and derivatives
Medchemexpress LLC Phthalazine | 253-52-1 | 130.15 | 100 G
Phthalazine is a nitrogen-containing organic heterocyclic compound and a substrate for human aldehyde oxidase 1, which can lead to the production of reactive oxygen species (ROS) and subsequent enzyme inactivation. It also exhibits antitumor activity.
- Nitrogen-containing organic heterocyclic compound
- Substrate for human aldehyde oxidase 1
- Leads to the production of reactive oxygen species (ROS) and subsequent enzyme inactivation
- Exhibits antitumor activity in various cancers
eMolecules 6-ETHYL-3-PYRIDAZINONE | 51355-93-2 | MFCD11520594 | 1g
AstaTech | 6-ETHYL-3-PYRIDAZINONE | 1g | 494131487 | 65671 | 97.000 | 51355-93-2 | MFCD11520594 | 124.143 | C6H8N2O
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eMolecules (S)-8-METHYLCHROMAN-4-AMINE | 1213596-97-4 | MFCD07374030 | 1g
AstaTech | (S)-8-METHYLCHROMAN-4-AMINE | 1g | 448263278 | Y11840 | 95.000 | 1213596-97-4 | MFCD07374030 | 163.220 | C10H13NO
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Medchemexpress LLC Phthalazinone pyrazole | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 10MM 1ML
Phthalazinone pyrazole is a potent, selective Aurora-A kinase inhibitor (IC50 = 0.031 μM) reported to arrest mitosis, induce apoptosis in proliferating cells, and suppress epithelial-mesenchymal transition during hepatocyte-like cell differentiation. It is supplied as a DMSO solution or as solid powder for research use.
- Potent, selective Aurora-A kinase inhibitor (IC50 = 0.031 μM).
- Reported to arrest mitosis and induce apoptosis in proliferating cells.
- Suppresses epithelial-mesenchymal transition during cell differentiation.
- Available as 10 mM in DMSO (1 mL) and multiple solid sizes.
- Molecular formula C18H15N5O; molecular weight 317.34.
- Purity 98.0%; store solid at 4°C protected from light; in solution store at -80°C (6 months) or -20°C (1 month).
eMolecules 932-22-9 | 4,5-Dichloro-pyridazin-3-ol | MFCD00006468 | 5g
Combi-Blocks | 4,5-Dichloro-pyridazin-3-ol | 5g | 117567794 | ST-0776 | 98.000 | 932-22-9 | MFCD00006468 | 164.970 | C4H2Cl2N2O
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Chemscene ChemScene | 3-Oxo-2,3-dihydropyridazine-4-carboxylic acid | 1G | CS-W003292 | 0.98 | 54404-06-7| MFCD06447027 | 140.1
ChemScene | 3-Oxo-2,3-dihydropyridazine-4-carboxylic acid | 1G | CS-W003292 | 0.98 | 54404-06-7| MFCD06447027 | 140.1
Medchemexpress LLC Phthalazine | 253-52-1 | 130.15 | 10 G
Phthalazine is a nitrogen-containing organic heterocyclic compound that serves as a substrate for human aldehyde oxidase 1, which leads to the production of reactive oxygen species (ROS) and subsequent enzyme inactivation. It has demonstrated antitumor activity in various cancers, including blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer.
- Substrate for human aldehyde oxidase 1
- Can lead to ROS production and enzyme inactivation
- Nitrogen-containing organic heterocyclic compound
- Exhibits antitumor activity in multiple cancer types
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Appears as a yellow to brown solid